Joshua was selected for a spotlight talk at the ASBMB Annual Meeting!!

January 20, 2023 – Fantastic news! Joshua submitted the first abstract of the lab for the Annual Meeting of the American Society for Biochemistry and Molecular Biology, and he was selected to give a 12-minute talk with 3 minutes of Q&A. This will be his first ever presentation at a national/international meeting, and the lab will be in beautiful Seattle to support him on March 25-28.

Fluorescence lifetime imaging (FLIM) in the lab!!

December 22, 2022 – Christmas presents arrived early for the lab! We now have the ability to resolve different fluorophores based on their fluorescence lifetimes, which allow us to simultaneously image up to 8 fluorescent proteins. Our new FLIM capabilities also allow us to assess changes in protein-protein interactions in live cells using Förster resonance energy transfer (FRET).

Happy 1-year Josh!!

September 9, 2022 – Happy one year anniversary to Josh, our energetic postdoc! We celebrated with our first joint lab happy hour with the fun Benham-Pyle team!! Some good chatter over cocktails, beer, and tasty appetizers!

Welcome Paola and Noah!

June 1, 2022 – We’re excited to have Paola and Noah join the team! Paola just graduated from the University of Oklahoma and is joining us as a research technician. She will be searching for factors that regulate contact sites between the ER and P-bodies. Noah is joining us as the first graduate student of the lab. He will be investigating mechanisms regulating the crosstalk between mRNA translation and mRNA silencing at the ER-condensate interface.

Resolving Bax-Drp1 interactions during apoptosis published in EMBOJ!

January 13, 2022 – Ana Garcia-Saez and team published a beautiful story showing physical interactions between Bax and Drp1 on mitochondrial membranes during apoptosis. This interaction plays a critical role in mediating the release of cytochrome C into the cytoplasm to potentiate the cell death cascade. Jason’s development of the dimerization dependent fluorescent biosensors (ddFBs) to resolve endoplasmic reticulum and processing (P)-body contact sites overlapped with Raquel Salvador-Gallego’s (Ana’s PhD student) time in the Voeltz Lab. Our collaboration fostered the use of ddFBs in the spatiotemporal resolution of Bax and Drp1 interactions on mitochondrial membranes upon the initiation of cell death. Check it out at EMBOJ!

Figure 1E from Jenner et al. EMBOJ (2022) of HeLa cells expressing RA-Bax, GB-Drp1, MitoBFP. The interactions between Bax and Drp1 are pseudocolored in green. The general mitochondrial marker is pseudocolored in magenta. Experiments above were conducted by Raquel Salvador-Gallego.

Joshua has been awarded a NIEHS T32 Fellowship!!

January 1, 2022 – Happy New Year and great news! Joshua Marcus, Ph.D. gave an excellent presentation of his preliminary studies in the J. Lee Lab and was selected to a one year appointment with The Precision Environmental Health Sciences (TPEHS) T32 Fellowship Program with the National Institute of Environmental Health Sciences (NIEHS). Joshua will be studying the effects of environmental stress on cytoplasmic organization with a focus on interactions between the endoplasmic reticulum and stress granules.

Our TurboID Mass Spec samples arrived safely in San Diego!!

December 15, 2021 – Jason combined work and play to drive the lab’s 85! samples to our collaborator in San Diego. There, he met his partner and daughter to spend several days at the beach to celebrate their daughter’s 3rd birthday. Pictured is moonset (City of Rocks State Park, New Mexico), which was captured on his solo drive back to Houston.


1st Holiday Party

December 17, 2021 – We celebrated a fun and productive 2021 with our first lab holiday party! Steaks, salmon, roasted veggies, mushroom risotto and carrot cake filled our bellies. It was great to hear everyone’s stories and to see that the lab chemistry experiment has successful beginnings. Here’s to more growth in 2022!