Leyla presented a 25 minute talk at BCM RNA club!

October 30, 2023 – Leyla presented her work developing a FLIM-FRET approach to monitor protein interactions within membrane-less condensates to the RNA community in the Texas Medical Center. She did an excellent job to communicate the concepts, approach and results, which fostered rich discussion and great questions. Importantly, RNA club gave Leyla the opportunity toContinue reading “Leyla presented a 25 minute talk at BCM RNA club!”

Our lab was awarded a NIH NIGMS R35 Grant!!!

July 19, 2023 – We have our first NIH grant from the National Institute of General Medical Sciences! This grant will provide $1.25M in funding over 5 years to support our research on elucidating the factors and function of ER contact sites with membrane-less organelles! We celebrated with Brazilian BBQ! Farewell to Zach!! June 6,Continue reading “Our lab was awarded a NIH NIGMS R35 Grant!!!”

Fluorescence lifetime imaging (FLIM) in the lab!!

December 22, 2022 – Christmas presents arrived early for the lab! We now have the ability to resolve different fluorophores based on their fluorescence lifetimes, which allow us to simultaneously image up to 8 fluorescent proteins. Our new FLIM capabilities also allow us to assess changes in protein-protein interactions in live cells using Förster resonanceContinue reading “Fluorescence lifetime imaging (FLIM) in the lab!!”

Happy 1-year Josh!!

September 9, 2022 – Happy one year anniversary to Josh, our energetic postdoc! We celebrated with our first joint lab happy hour with the fun Benham-Pyle team!! Some good chatter over cocktails, beer, and tasty appetizers!

Resolving Bax-Drp1 interactions during apoptosis published in EMBOJ!

January 13, 2022 – Ana Garcia-Saez and team published a beautiful story showing physical interactions between Bax and Drp1 on mitochondrial membranes during apoptosis. This interaction plays a critical role in mediating the release of cytochrome C into the cytoplasm to potentiate the cell death cascade. Jason’s development of the dimerization dependent fluorescent biosensors (ddFBs)Continue reading “Resolving Bax-Drp1 interactions during apoptosis published in EMBOJ!”

Joshua has been awarded a NIEHS T32 Fellowship!!

January 1, 2022 – Happy New Year and great news! Joshua Marcus, Ph.D. gave an excellent presentation of his preliminary studies in the J. Lee Lab and was selected to a one year appointment with The Precision Environmental Health Sciences (TPEHS) T32 Fellowship Program with the National Institute of Environmental Health Sciences (NIEHS). Joshua willContinue reading “Joshua has been awarded a NIEHS T32 Fellowship!!”

Our TurboID Mass Spec samples arrived safely in San Diego!!

December 15, 2021 – Jason combined work and play to drive the lab’s 85! samples to our collaborator in San Diego. There, he met his partner and daughter to spend several days at the beach to celebrate their daughter’s 3rd birthday. Pictured is moonset (City of Rocks State Park, New Mexico), which was captured onContinue reading “Our TurboID Mass Spec samples arrived safely in San Diego!!”